Interactor 1: CDC23 (Q9UJX2)
Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8)
Gene: CDC23

Interactor 2: APC5 (Q9UJX4)
Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5)
Gene: ANAPC5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.900

The method score is based on:

Property Details
Experiments 26496610, 35271311, 33961781, 20360068
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC5~TPR_11
Common GO terms GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007346 - regulation of mitotic cell cycle
GO:0031145 - anaphase-promoting complex-dependent catabolic process
and 4 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 597
Hs

1 755
+ Hs
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+ Sc
+ Sp
+ Sc
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+ Xl
+ At
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Last updated: 15 Jul 2024