HitPredict

Interactor 1: CDC23 (Q9UJX2)
Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8)
Gene: CDC23

Interactor 2: ANC2 (Q9UJX6)
Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2)
Gene: ANAPC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.729

The method score is based on:

Property Details
Experiments 26496610, 35271311, 10922056, 12956947, 34079125, 20360068
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007091 - metaphase/anaphase transition of mitotic cell cycle
GO:0007346 - regulation of mitotic cell cycle
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 597
Hs

1 822
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+ Xl

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Last updated: 15 Jul 2024