Interactor 1: APC4 (Q9UJX5)
Anaphase-promoting complex subunit 4 (APC4) (Cyclosome subunit 4)
Gene: ANAPC4

Interactor 2: ANC2 (Q9UJX6)
Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2)
Gene: ANAPC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 10922056, 12956947, 34079125, 35271311, 26083744, 25490258, 25673878, 29549242, 23078409, 25043029
Identification Methods affinity chromatography technology, proximity labelling technology, pull down, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC4~Cullin
Common GO terms GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007346 - regulation of mitotic cell cycle
GO:0031145 - anaphase-promoting complex-dependent catabolic process
and 3 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 808
Hs

1 822
+ Hs
+ At
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024