HitPredict

Interactor 1: HSPB8 (Q9UJY1)
Heat shock protein beta-8 (HspB8) (Alpha-crystallin C chain) (E2-induced gene 1 protein) (Heat shock protein family B member 8) (Protein kinase H11) (Small stress protein-like protein HSP22)
Gene: HSPB8

Interactor 2: MYH2 (Q9UKX2)
Myosin-2 (Myosin heavy chain 2) (Myosin heavy chain 2a) (MyHC-2a) (Myosin heavy chain IIa) (MyHC-IIa) (Myosin heavy chain, skeletal muscle, adult 2)
Gene: MYH2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 1941
+	Hs
		522580 HSPB8_HUMAN (1-196): 7.92e-71: 214: 100.00		MYH1_HUMAN (1-1941): 0: 1115: 94.54
+	Hs
		1356186 HSPB8_HUMAN (1-196): 7.92e-71: 214: 100.00		MYH4_HUMAN (1-1941): 0: 1113: 91.40
+	Hs
		528397 HSPB8_HUMAN (1-196): 7.92e-71: 214: 100.00		MYH6_HUMAN (3-1933): 0: 1090: 80.22
+	Hs
		61510 HSPB2_HUMAN (1-170): 5.01e-42: 141: 25.88		A5YM51_HUMAN (3-1933): 0: 1123: 81.05
+	Hs
		528375 HSPB2_HUMAN (1-170): 5.01e-42: 141: 25.88		MYH6_HUMAN (3-1933): 0: 1090: 80.22
+	Hs
		528430 HSPB8_HUMAN (1-196): 7.92e-71: 214: 100.00		MYH8_HUMAN (931-1941): 1.18e-60: 233: 17.85
+	Dm
		404257 Q9VSA9_DROME (37-193): 1.51e-35: 124: 24.68		MYSA_DROME (1003-1940): 3e-60: 232: 17.48
+	Dm
		113819 M9NHC5_DROME (67-172): 1.81e-32: 115: 27.36		MYSA_DROME (1003-1940): 3e-60: 232: 17.48
+	Hs
		502931 HSPB8_HUMAN (1-196): 7.92e-71: 214: 100.00		MYH3_HUMAN (732-1213): 4.32e-15: 84: 13.31