HitPredict

Interactor 1: ZN223 (Q9UK11)
Zinc finger protein 223
Gene: ZNF223

Interactor 2: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 482 Hs			1 2610
+	Hs
		1354550 ZN629_HUMAN (57-340): 8.22e-45: 169: 16.78		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		304387 ZN223_HUMAN (1-482): 0: 678: 100.00		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		304262 ZN480_HUMAN (1-480): 0: 614: 35.85		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		304388 ZN222_HUMAN (1-481): 0: 562: 73.60		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		304128 ZNF45_HUMAN (73-317): 2.23e-78: 259: 36.33		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		304184 ZNF74_HUMAN (274-473): 3.29e-45: 169: 43.00		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		304140 ZN543_HUMAN (57-157): 1.1e-18: 90.9: 9.62		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		1059444 ZN846_HUMAN (50-146): 4.56e-13: 73.2: 8.00		WWP1_HUMAN (2328-2608): 5.47e-91: 321: 29.27
+	Hs
		549151 ZN250_HUMAN (56-118): 5.77e-09: 60.4: 4.76		UBE3A_HUMAN (2406-2607): 5.17e-25: 116: 34.95