HitPredict

Interactor 1: FBW1B (Q9UKB1)
F-box/WD repeat-containing protein 11 (F-box and WD repeats protein beta-TrCP2) (F-box/WD repeat-containing protein 1B) (Homologous to Slimb protein) (HOS)
Gene: FBXW11

Interactor 2: RPGF2 (Q9Y4G8)
Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1)
Gene: RAPGEF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25332235, 25515538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0043005 - neuron projection GO:0043025 - neuronal cell body
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 542 Hs			1 1499
+	Hs
		1377163 FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59		RPGF2_HUMAN (1-1499): 0: 1710: 100.00
+	Hs
		1047054 FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00		RPGF1_HUMAN (497-962): 7.1e-99: 345: 19.96
+	Hs
		1047055 FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59		RPGF1_HUMAN (497-962): 7.1e-99: 345: 19.96