HitPredict

Interactor 1: TLK1 (Q9UKI8)
Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (PKU-beta) (Tousled-like kinase 1)
Gene: TLK1

Interactor 2: TLK1 (Q9UKI8)
Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (PKU-beta) (Tousled-like kinase 1)
Gene: TLK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.902

The method score is based on:

Property Details
Experiments 25416956, 16189514, 10523312, 12955071
Identification Methods two hybrid, enzymatic study, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006325 - chromatin organization
and 7 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 766
Hs

1 766
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024