Interactor 1: AGO2 (Q9UKV8)
Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer)
Gene: AGO2

Interactor 2: AGO2 (Q9UKV8)
Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer)
Gene: AGO2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 25681748
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ArgoL1~ArgoL1, ArgoL1~ArgoL2, ArgoL1~ArgoN, ArgoL1~PAZ, ArgoL1~Piwi, ArgoL2~ArgoMid, ArgoL2~ArgoN, ArgoL2~PAZ, ArgoL2~Piwi, ArgoMid~ArgoMid, ArgoMid~Piwi, ArgoN~Piwi, PAZ~PAZ, PAZ~Piwi, Piwi~Piwi
Common GO terms GO:0000340 - RNA 7-methylguanosine cap binding
GO:0000932 - P-body
GO:0000993 - RNA polymerase II complex binding
GO:0001046 - core promoter sequence-specific DNA binding
GO:0003723 - RNA binding
and 42 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 859
Hs

1 859
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Zm
+ Mm
+ Dr
+ Dm
+ Dm

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Last updated: 15 Jul 2024