HitPredict

Interactor 1: AGO1 (Q9UL18)
Protein argonaute-1 (Argonaute1) (hAgo1) (Argonaute RISC catalytic component 1) (Eukaryotic translation initiation factor 2C 1) (eIF-2C 1) (eIF2C 1) (Putative RNA-binding protein Q99)
Gene: AGO1

Interactor 2: DICER (Q9UPY3)
Endoribonuclease Dicer (EC 3.1.26.3) (Helicase with RNase motif) (Helicase MOI)
Gene: DICER1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.949

The method score is based on:

Property Details
Experiments 33961781, 17932509, 19716330, 24778252, 12906857, 12526743
Identification Methods affinity chromatography technology, coimmunoprecipitation, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ArgoL1~PAZ, ArgoL2~PAZ, PAZ~PAZ, PAZ~Ribonuclease_3, PAZ~Piwi
Common GO terms GO:0003723 - RNA binding
GO:0003725 - double-stranded RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 857
Hs

1 1922
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+ Dm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024