HitPredict

Interactor 1: AGO1 (Q9UL18)
Protein argonaute-1 (Argonaute1) (hAgo1) (Argonaute RISC catalytic component 1) (Eukaryotic translation initiation factor 2C 1) (eIF-2C 1) (eIF2C 1) (Putative RNA-binding protein Q99)
Gene: AGO1

Interactor 2: SF3B6 (Q9Y3B4)
Splicing factor 3B subunit 6 (Pre-mRNA branch site protein p14) (SF3b 14 kDa subunit) (SF3B14a) (Spliceosome-associated protein, 14-kDa) (Splicing factor 3b, subunit 6, 14kDa)
Gene: SF3B6

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	17932509
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 857 Hs			1 125
+	Hs
		1334297 AGO3_HUMAN (1-857): 0: 1189: 83.83		SF3B6_HUMAN (1-125): 2.65e-49: 154: 100.00
+	Hs
		1329989 AGO1_HUMAN (1-857): 0: 1222: 100.00		PABP3_HUMAN (20-99): 3.04e-21: 89.5: 23.46
+	Hs
		516737 AGO1_HUMAN (1-857): 0: 1222: 100.00		PABP1_HUMAN (20-99): 4.52e-21: 89.1: 23.46
+	Mm
		1208650 AGO2_MOUSE (3-857): 0: 1213: 82.36		Q99LF8_MOUSE (12-99): 1.34e-22: 93.3: 22.47
+	Mm
		665763 AGO2_MOUSE (3-857): 0: 1213: 82.36		PABP1_MOUSE (20-99): 4.75e-21: 89.1: 23.46
+	Hs
		516735 AGO2_HUMAN (19-857): 0: 1206: 83.43		PABP1_HUMAN (20-99): 4.52e-21: 89.1: 23.46
+	Hs
		516695 AGO3_HUMAN (1-857): 0: 1189: 83.83		PABP1_HUMAN (20-99): 4.52e-21: 89.1: 23.46
+	Hs
		1031470 AGO4_HUMAN (9-857): 0: 1167: 83.04		PABP4_HUMAN (12-99): 1.35e-22: 93.3: 22.47
+	Hs
		516701 AGO4_HUMAN (9-857): 0: 1167: 83.04		PABP1_HUMAN (20-99): 4.52e-21: 89.1: 23.46