HitPredict

Interactor 1: DNM1L (O00429)
Dynamin-1-like protein (EC 3.6.5.5) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-like protein) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV) (Dynamin-related protein 1)
Gene: DNM1L

Interactor 2: MID49 (Q96C03)
Mitochondrial dynamics protein MID49 (Mitochondrial dynamics protein of 49 kDa) (Mitochondrial elongation factor 2) (Smith-Magenis syndrome chromosomal region candidate gene 7 protein)
Gene: MIEF2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	23530241, 29464060, 29899447, 21508961
Identification Methods	pull down, anti bait coimmunoprecipitation, 3D electron microscopy, two hybrid, cross-linking study
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0007005 - mitochondrion organization GO:0090141 - positive regulation of mitochondrial fission
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 736 Hs			1 454
+	Mm
		1208437 DNM1L_MOUSE (1-736): 0: 901: 98.64		MID49_MOUSE (1-454): 0: 732: 79.74
+	Mm
		1296507 DNM1L_MOUSE (1-736): 0: 901: 98.64		MID51_MOUSE (1-454): 0: 706: 45.38
+	Hs
		135705 DNM1L_HUMAN (1-736): 0: 902: 100.00		MID51_HUMAN (1-454): 0: 701: 45.38