Interactor 1: TRPC5 (Q9UL62)
Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (TRP-5) (hTRP-5) (hTRP5)
Gene: TRPC5

Interactor 2: TRPC6 (Q9Y210)
Short transient receptor potential channel 6 (TrpC6) (Transient receptor protein 6) (TRP-6)
Gene: TRPC6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 12857742
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~Ank_2, Ank_2~Ank_2, Ank_2~TRP_2, Ion_trans~Ion_trans
Common GO terms GO:0005262 - calcium channel activity
GO:0005886 - plasma membrane
GO:0007204 - positive regulation of cytosolic calcium ion concentration
GO:0015279 - store-operated calcium channel activity
GO:0034703 - cation channel complex
and 3 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 973
Hs

1 931
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Dm
+ Dm
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024