HitPredict

Interactor 1: BRPF3 (Q9ULD4)
Bromodomain and PHD finger-containing protein 3
Gene: BRPF3

Interactor 2: ING4 (Q9UNL4)
Inhibitor of growth protein 4 (p29ING4)
Gene: ING4

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	31753913, 24981860
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EPL1~ING
Common GO terms	GO:0000123 - histone acetyltransferase complex GO:0005634 - nucleus GO:0005829 - cytosol GO:0006338 - chromatin remodeling GO:0006355 - regulation of DNA-templated transcription and 1 others more... GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1205 Hs			1 249
+	Hs
		1264497 BRPF3_HUMAN (1-1205): 0: 999: 100.00		ING5_HUMAN (1-249): 6.7e-86: 257: 67.87
+	Hs
		1348038 BRPF3_HUMAN (1-1205): 0: 999: 100.00		ING3_HUMAN (180-249): 2.39e-32: 123: 57.14
+	Hs
		876727 BRPF1_HUMAN (1-1202): 0: 813: 48.20		ING4_HUMAN (1-249): 7.49e-98: 287: 100.00
+	Hs
		876708 BRPF1_HUMAN (1-1202): 0: 813: 48.20		ING5_HUMAN (1-249): 6.7e-86: 257: 67.87
+	Hs
		876726 BRPF1_HUMAN (1-1202): 0: 813: 48.20		ZMYD8_HUMAN (125-244): 1.26e-19: 89.6: 22.39
+	Hs
		1152696 JADE1_HUMAN (6-632): 1.24e-105: 354: 24.73		ING4_HUMAN (1-249): 7.49e-98: 287: 100.00
+	Hs
		1152683 JADE1_HUMAN (6-632): 1.24e-105: 354: 24.73		ING5_HUMAN (1-249): 6.7e-86: 257: 67.87
+	Hs
		1268057 JADE3_HUMAN (1-617): 3.63e-92: 317: 25.83		ING4_HUMAN (1-249): 7.49e-98: 287: 100.00
+	Hs
		1343287 JADE2_HUMAN (10-602): 3.25e-91: 313: 23.58		ING4_HUMAN (1-249): 7.49e-98: 287: 100.00
+	Hs
		2717 A0A0C4DFT8_HUMAN (10-600): 1.47e-90: 311: 23.49		ING4_HUMAN (1-249): 7.49e-98: 287: 100.00
+	Hs
		1264466 JADE3_HUMAN (1-617): 3.63e-92: 317: 25.83		ING5_HUMAN (1-249): 6.7e-86: 257: 67.87
+	Hs
		1264487 JADE2_HUMAN (10-602): 3.25e-91: 313: 23.58		ING5_HUMAN (1-249): 6.7e-86: 257: 67.87
+	Hs
		2713 A0A0C4DFT8_HUMAN (10-600): 1.47e-90: 311: 23.49		ING5_HUMAN (1-249): 6.7e-86: 257: 67.87
+	Hs
		319380 BRD1_HUMAN (680-1202): 1.71e-77: 279: 28.32		ING4_HUMAN (1-249): 7.49e-98: 287: 100.00
+	Hs
		319285 BRD1_HUMAN (680-1202): 1.71e-77: 279: 28.32		ING5_HUMAN (1-249): 6.7e-86: 257: 67.87
+	Sc
		995740 NTO1_YEAST (59-654): 4.2e-96: 326: 24.72		YNG1_YEAST (10-245): 1.11e-42: 146: 22.88
+	Dm
		1177410 BRDH_DROME (875-1193): 2.6e-62: 235: 26.88		ING5_DROME (1-249): 1.49e-73: 227: 46.34
+	Hs
		1268053 JADE3_HUMAN (1-617): 3.63e-92: 317: 25.83		ING3_HUMAN (180-249): 2.39e-32: 123: 57.14
+	Hs
		1343284 JADE2_HUMAN (10-602): 3.25e-91: 313: 23.58		ING3_HUMAN (180-249): 2.39e-32: 123: 57.14
+	Hs
		1139022 PHIP_HUMAN (355-1050): 3.1e-67: 251: 13.05		TAF3_HUMAN (112-244): 6.36e-23: 99.2: 22.15