HitPredict

Interactor 1: CNOT6 (Q9ULM6)
CCR4-NOT transcription complex subunit 6 (EC 3.1.13.4) (CCR4 carbon catabolite repression 4-like) (Carbon catabolite repressor protein 4 homolog) (Cytoplasmic deadenylase)
Gene: CNOT6

Interactor 2: TNR6B (Q9UPQ9)
Trinucleotide repeat-containing gene 6B protein
Gene: TNRC6B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	21981923, 29395067
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol GO:0035195 - miRNA-mediated post-transcriptional gene silencing
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 557 Hs			1 1833
+	Hs
		1297142 CNO6L_HUMAN (1-557): 4.95e-126: 382: 77.38		TNR6B_HUMAN (28-1833): 0: 1086: 100.00
+	Hs
		1242694 CNOT6_HUMAN (1-557): 4.14e-143: 426: 100.00		TNR6A_HUMAN (2-1833): 0: 785: 35.34
+	Hs
		1242633 CNO6L_HUMAN (1-557): 4.95e-126: 382: 77.38		TNR6A_HUMAN (2-1833): 0: 785: 35.34
+	Hs
		1336211 CNOT6_HUMAN (1-557): 4.14e-143: 426: 100.00		TNR6C_HUMAN (34-1830): 0: 655: 34.21
+	Hs
		1297131 CNO6L_HUMAN (1-557): 4.95e-126: 382: 77.38		TNR6C_HUMAN (34-1830): 0: 655: 34.21
+	Dm
		1213159 Q8IMX1_DROME (26-557): 7.19e-130: 392: 56.39		GAWKY_DROME (615-1735): 3.49e-145: 488: 21.36
+	Hs
		1284131 LRC59_HUMAN (47-132): 4.49e-13: 72: 47.67		RRBP1_HUMAN (6-689): 6.03e-33: 142: 10.09