HitPredict

Interactor 1: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 23972993, 32345958
Identification Methods enzymatic study, affinity chromatography technology, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC4_WD40~WD40
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:1904668 - positive regulation of ubiquitin protein ligase activity
GO:1990756 - ubiquitin-like ligase-substrate adaptor activity
GO:1990757 - ubiquitin ligase activator activity
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 496
Hs

1 605
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024