Interactor 1: NOTC3 (Q9UM47)
Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain]
Gene: NOTCH3
Interactor 2: JAG2 (Q9Y219)
Protein jagged-2 (Jagged2) (hJ2)
Gene: JAG2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11006133 |
| Identification Methods | pull down |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EGF~EGF, EGF~EGF_CA, DSL~EGF_CA, EGF_CA~EGF_CA, EGF_CA~MNNL |
| Common GO terms | GO:0005112 - Notch binding GO:0005509 - calcium ion binding GO:0005886 - plasma membrane GO:0007219 - Notch signaling pathway |
| Homologous interactions | 18 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
