Interactor 1: UBP18 (Q9UMW8)
Ubl carboxyl-terminal hydrolase 18 (EC 3.4.19.12) (43 kDa ISG15-specific protease) (hUBP43) (ISG15-specific-processing protease) (Ubl thioesterase 18)
Gene: USP18

Interactor 2: SAMH1 (Q9Y3Z3)
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-) (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5) (SAM domain and HD domain-containing protein 1) (hSAMHD1)
Gene: SAMHD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 30068654
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0060339 - negative regulation of type I interferon-mediated signaling pathway
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 372
Hs

1 626
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024