Interactor 1: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1
Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.98 | 1.00 | 0.994 |
The method score is based on:
Property | Details |
---|---|
Experiments | 25258038, 25684577, 26330542, 26010904, 17426036, 28134249, 28757353, 29091030, 28396517, 28496195, 28852129, 23695783, 29317501, 31596601, 32723828, 34057440, 18485199, 35398354, 36027913, 36481767 and 12 others
more... |
Identification Methods | enzymatic study, pull down, affinity chromatography technology, protein complementation assay |
Interaction Type | direct interaction, physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | ANAPC3~ANAPC3, ANAPC3~CHIP_TPR_N, CHIP_TPR_N~CHIP_TPR_N, CHIP_TPR_N~U-box, U-box~U-box |
Common GO terms | GO:0000151 - ubiquitin ligase complex GO:0000165 - MAPK cascade GO:0000209 - protein polyubiquitination GO:0001664 - G protein-coupled receptor binding GO:0002931 - response to ischemia and 55 others more... |
Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024