HitPredict

Interactor 1: PACN2 (Q9UNF0)
Protein kinase C and casein kinase substrate in neurons protein 2 (Syndapin-2) (Syndapin-II) (SdpII)
Gene: PACSIN2

Interactor 2: PACN2 (Q9UNF0)
Protein kinase C and casein kinase substrate in neurons protein 2 (Syndapin-2) (Syndapin-II) (SdpII)
Gene: PACSIN2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 25416956, 16189514, 32296183, 11082044, 31515488, unassigned1304, 20188097
Identification Methods two hybrid, pull down, two hybrid array, two hybrid prey pooling approach, validated two hybrid, two hybrid pooling approach, x-ray crystallography
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FCH~FCH, FCH~SH3_9, SH3_9~SH3_9
Common GO terms GO:0005543 - phospholipid binding
GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005769 - early endosome
GO:0005829 - cytosol
and 24 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024