HitPredict

Interactor 1: SNX7 (Q9UNH6)
Sorting nexin-7
Gene: SNX7

Interactor 2: SNX6 (Q9UNH7)
Sorting nexin-6 (TRAF4-associated factor 2) [Cleaved into: Sorting nexin-6, N-terminally processed]
Gene: SNX6

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	23085988
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PX~PX, PX~Vps5
Common GO terms	GO:0031901 - early endosome membrane GO:0035091 - phosphatidylinositol binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 387 Hs			1 406
+	Hs
		240456 SNX2_HUMAN (3-378): 7.54e-94: 292: 21.38		SNX6_HUMAN (1-406): 6.83e-126: 371: 100.00
+	Hs
		1040533 SNX1_HUMAN (1-377): 2.49e-85: 270: 19.61		SNX6_HUMAN (1-406): 6.83e-126: 371: 100.00
+	Hs
		240464 SNX2_HUMAN (3-378): 7.54e-94: 292: 21.38		SNX5_HUMAN (13-405): 3.75e-112: 336: 64.38
+	Hs
		240410 SNX2_HUMAN (3-378): 7.54e-94: 292: 21.38		SNX32_HUMAN (23-405): 1.38e-106: 321: 70.47
+	Hs
		1040543 SNX1_HUMAN (1-377): 2.49e-85: 270: 19.61		SNX5_HUMAN (13-405): 3.75e-112: 336: 64.38
+	Hs
		1139039 SNX30_HUMAN (20-372): 9.33e-88: 273: 49.01		SNX32_HUMAN (23-405): 1.38e-106: 321: 70.47
+	Hs
		1040476 SNX1_HUMAN (1-377): 2.49e-85: 270: 19.61		SNX32_HUMAN (23-405): 1.38e-106: 321: 70.47
+	Dm
		1370164 Q9VQQ6_DROME (7-377): 1.01e-85: 269: 17.16		Q9VLQ9_DROME (28-403): 6.48e-105: 319: 55.97
+	Hs
		240317 SNX2_HUMAN (3-378): 7.54e-94: 292: 21.38		SNX2_HUMAN (16-404): 1.6e-93: 292: 21.31
+	Dm
		112640 X2J8I7_DROME (7-377): 2.41e-84: 265: 17.24		M9NDI3_DROME (28-403): 2.82e-102: 312: 54.83
+	Hs
		240386 SNX2_HUMAN (3-378): 7.54e-94: 292: 21.38		SNX1_HUMAN (32-404): 3.57e-86: 273: 20.96
+	Hs
		1040456 SNX1_HUMAN (1-377): 2.49e-85: 270: 19.61		SNX1_HUMAN (32-404): 3.57e-86: 273: 20.96
+	Hs
		307918 SNX7_HUMAN (1-387): 7.12e-109: 326: 100.00		SNX4_HUMAN (14-403): 5e-57: 195: 15.54
+	Hs
		1139037 SNX30_HUMAN (20-372): 9.33e-88: 273: 49.01		SNX30_HUMAN (21-403): 2.2e-75: 242: 15.42
+	Hs
		1261054 SNX9_HUMAN (28-373): 4e-78: 253: 16.34		SNX33_HUMAN (24-404): 1.43e-80: 260: 12.47
+	Hs
		240322 SNX2_HUMAN (3-378): 7.54e-94: 292: 21.38		SNX4_HUMAN (14-403): 5e-57: 195: 15.54
+	Hs
		1300858 SNX9_HUMAN (28-373): 4e-78: 253: 16.34		SNX18_HUMAN (24-359): 2.59e-67: 226: 11.57
+	Hs
		307895 SNX30_HUMAN (20-372): 9.33e-88: 273: 49.01		SNX4_HUMAN (14-403): 5e-57: 195: 15.54
+	Hs
		1040542 SNX1_HUMAN (1-377): 2.49e-85: 270: 19.61		SNX8_HUMAN (39-403): 5.41e-54: 187: 16.54