HitPredict

Interactor 1: ING4 (Q9UNL4)
Inhibitor of growth protein 4 (p29ING4)
Gene: ING4

Interactor 2: ING4 (Q9UNL4)
Inhibitor of growth protein 4 (p29ING4)
Gene: ING4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	1.00	0.886

The method score is based on:

Property	Details
Experiments	23624912, 20445261, 20053357, 22334692
Identification Methods	enzymatic study, x-ray crystallography, affinity chromatography technology
Interaction Type	direct interaction, association, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	ING~ING
Common GO terms	GO:0000123 - histone acetyltransferase complex GO:0001558 - regulation of cell growth GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm and 18 others more... GO:0005829 - cytosol GO:0006338 - chromatin remodeling GO:0006355 - regulation of DNA-templated transcription GO:0006473 - protein acetylation GO:0006915 - apoptotic process GO:0007049 - cell cycle GO:0008285 - negative regulation of cell population proliferation GO:0035064 - methylated histone binding GO:0043065 - positive regulation of apoptotic process GO:0045111 - intermediate filament cytoskeleton GO:0045892 - negative regulation of DNA-templated transcription GO:0045926 - negative regulation of growth GO:0046872 - metal ion binding GO:0051726 - regulation of cell cycle GO:0140889 - DNA replication-dependent chromatin disassembly GO:1902164 - positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:1902749 - regulation of cell cycle G2/M phase transition GO:2000278 - regulation of DNA biosynthetic process
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	249
Hs

1	249

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Hs

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Zm

+

Hs

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Sc

+

Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024