HitPredict

Interactor 1: FAF1 (Q9UNN5)
FAS-associated factor 1 (hFAF1) (UBX domain-containing protein 12) (UBX domain-containing protein 3A)
Gene: FAF1

Interactor 2: NSF1C (Q9UNZ2)
NSFL1 cofactor p47 (UBX domain-containing protein 2C) (p97 cofactor p47)
Gene: NSFL1C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	26389662, 28443643
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UBA_4~UBA_4, UBX~UBX
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043130 - ubiquitin binding GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 650 Hs			1 370
+	Hs
		1062091 FAF1_HUMAN (1-650): 0: 840: 100.00		UBX2B_HUMAN (17-369): 7.87e-132: 381: 48.44
+	Hs
		935740 FAF1_HUMAN (1-650): 0: 840: 100.00		UBX2A_HUMAN (173-369): 1.15e-84: 259: 41.41
+	Hs
		299493 UBXN7_HUMAN (278-649): 4.64e-77: 255: 15.79		NSF1C_HUMAN (1-370): 9.9e-180: 505: 100.00
+	Hs
		1318425 UBXN6_HUMAN (395-645): 7.43e-34: 136: 15.73		NSF1C_HUMAN (1-370): 9.9e-180: 505: 100.00
+	Hs
		979377 UBXN1_HUMAN (414-649): 9.29e-34: 132: 16.00		NSF1C_HUMAN (1-370): 9.9e-180: 505: 100.00
+	Sp
		144231 UBX2_SCHPO (253-645): 1.49e-80: 263: 14.04		UBX3_SCHPO (4-368): 9.14e-108: 323: 27.99
+	Hs
		1062086 UBXN6_HUMAN (395-645): 7.43e-34: 136: 15.73		UBX2B_HUMAN (17-369): 7.87e-132: 381: 48.44
+	Sc
		710581 UBX5_YEAST (270-650): 6.39e-48: 177: 11.71		UBX1_YEAST (52-368): 8.1e-101: 306: 29.72
+	Sc
		710544 UBX7_YEAST (355-650): 1.65e-45: 169: 14.72		UBX1_YEAST (52-368): 8.1e-101: 306: 29.72
+	Hs
		935736 UBXN6_HUMAN (395-645): 7.43e-34: 136: 15.73		UBX2A_HUMAN (173-369): 1.15e-84: 259: 41.41