HitPredict

Interactor 1: SRPK3 (Q9UPE1)
SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)
Gene: SRPK3

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	23602568
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 567 Hs			1 2752
+	Hs
		625642 CDK2_HUMAN (274-566): 4.84e-82: 260: 17.97		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		943024 SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		1268608 DYRK2_HUMAN (344-565): 4.02e-65: 224: 25.82		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		807687 CDK3_HUMAN (76-371): 9.13e-81: 257: 17.28		MAP1B_HUMAN (15-1517): 8.71e-69: 261: 10.13
+	Hs
		942706 SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69		PRC2B_HUMAN (640-2750): 5.74e-64: 245: 9.36
+	Sp
		194038 DSK1_SCHPO (3-565): 8.43e-109: 338: 35.27		YFHH_SCHPO (1718-2751): 2.26e-16: 88.6: 9.25
+	Hs
		835653 GSK3B_HUMAN (23-336): 1.58e-67: 226: 16.87		MAP1A_HUMAN (170-2540): 2.1e-44: 181: 9.15
+	Hs
		65021 GSK3B_HUMAN (23-336): 1.58e-67: 226: 16.87		A7Y9J9_HUMAN (290-2748): 9.47e-43: 175: 9.11
+	Hs
		942890 SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69		MINT_HUMAN (709-2695): 5.55e-37: 157: 9.30
+	Hs
		835988 GSK3B_HUMAN (23-336): 1.58e-67: 226: 16.87		TARA_HUMAN (1540-2752): 1.5e-31: 138: 11.50
+	Hs
		1268591 DYRK2_HUMAN (344-565): 4.02e-65: 224: 25.82		TARA_HUMAN (1540-2752): 1.5e-31: 138: 11.50
+	Hs
		625528 CDK2_HUMAN (274-566): 4.84e-82: 260: 17.97		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Hs
		942845 SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Hs
		820880 SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		1264773 DYRK2_HUMAN (344-565): 4.02e-65: 224: 25.82		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Hs
		942911 SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69		DIDO1_HUMAN (13-1216): 9.01e-11: 70.1: 10.22
+	Hs
		943046 SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69		PRC2C_HUMAN (1360-2752): 9.55e-11: 70.1: 9.11
+	Hs
		311795 CLK2_HUMAN (60-227): 1.39e-63: 218: 32.54		TACC2_HUMAN (1893-2744): 4.03e-13: 78.2: 8.34
+	Hs
		70875 CLK2_HUMAN (60-227): 1.39e-63: 218: 32.54		B2RWP4_HUMAN (1893-2744): 4.01e-13: 78.2: 8.34
+	Hs
		836122 GSK3B_HUMAN (23-336): 1.58e-67: 226: 16.87		PRC2C_HUMAN (1360-2752): 9.55e-11: 70.1: 9.11