HitPredict

Interactor 1: WASF3 (Q9UPY6)
Actin-binding protein WASF3 (Protein WAVE-3) (Verprolin homology domain-containing protein 3) (Wiskott-Aldrich syndrome protein family member 3) (WASP family protein member 3)
Gene: WASF3

Interactor 2: NCKP1 (Q9Y2A7)
Nck-associated protein 1 (NAP 1) (Membrane-associated protein HEM-2) (p125Nap1)
Gene: NCKAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030027 - lamellipodium GO:0031209 - SCAR complex GO:0070062 - extracellular exosome GO:2000601 - positive regulation of Arp2/3 complex-mediated actin nucleation
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 502 Hs			1 1128
+	Hs
		1267042 WASF1_HUMAN (1-500): 3.42e-59: 206: 43.57		NCKP1_HUMAN (1-1128): 0: 1697: 100.00
+	Hs
		1377177 WASF2_HUMAN (1-484): 2.01e-57: 200: 43.60		NCKP1_HUMAN (1-1128): 0: 1697: 100.00
+	Bt
		94400 WASF1_BOVIN (1-500): 9.32e-59: 205: 43.93		F1MPZ9_BOVIN (1-1128): 0: 1691: 99.30
+	Mm
		659531 WASF1_MOUSE (1-500): 1.12e-58: 204: 43.21		NCKP1_MOUSE (1-1128): 0: 1691: 99.38
+	Hs
		876305 WASF2_HUMAN (1-484): 2.01e-57: 200: 43.60		NCKPL_HUMAN (4-1121): 0: 1560: 59.23
+	Dm
		94632 F2FB81_DROME (1-209): 1.43e-42: 162: 54.55		HEM_DROME (1-1122): 0: 1545: 59.57