HitPredict

Interactor 1: JIP1 (Q9UQF2)
C-Jun-amino-terminal kinase-interacting protein 1 (JIP-1) (JNK-interacting protein 1) (Islet-brain 1) (IB-1) (JNK MAP kinase scaffold protein 1) (Mitogen-activated protein kinase 8-interacting protein 1)
Gene: MAPK8IP1

Interactor 2: JIP1 (Q9UQF2)
C-Jun-amino-terminal kinase-interacting protein 1 (JIP-1) (JNK-interacting protein 1) (Islet-brain 1) (IB-1) (JNK MAP kinase scaffold protein 1) (Mitogen-activated protein kinase 8-interacting protein 1)
Gene: MAPK8IP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 10490659, 18286207
Identification Methods affinity chromatography technology, molecular sieving
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PID~PID, SH3_9~SH3_9
Common GO terms GO:0004860 - protein kinase inhibitor activity
GO:0005078 - MAP-kinase scaffold activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
and 18 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 711
Hs

1 711
+ Rn
+ Rn
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Dm
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024