Interactor 1: CSN4 (Q9V345)
COP9 signalosome complex subunit 4 (Dch4) (Signalosome subunit 4)
Gene: CSN4

Interactor 2: CSN5 (Q9XZ58)
COP9 signalosome complex subunit 5 (Dch5) (Signalosome subunit 5) (EC 3.4.-.-) (JAB1 homolog)
Gene: CSN5

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 25119050
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CSN4_RPN5_eIF3a~CSN5_C, CSN4_RPN5_eIF3a~JAB, JAB~PCI
Common GO terms GO:0000338 - protein deneddylation
GO:0001751 - compound eye photoreceptor cell differentiation
GO:0007281 - germ cell development
GO:0008180 - COP9 signalosome
GO:0032435 - negative regulation of proteasomal ubiquitin-dependent protein catabolic process
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 407
Dm

1 327
+ Mm
+ Hs
+ Dm
+ At
+ At
+ Mm
+ Hs
+ Ce
+ An
+ Dm
+ Dm
+ Hs
+ Hs
+ Sp
+ At
+ Hs
+ Dm
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024