HitPredict

Interactor 1: MA2B1 (O00754)
Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B) [Cleaved into: Lysosomal alpha-mannosidase A peptide; Lysosomal alpha-mannosidase B peptide; Lysosomal alpha-mannosidase C peptide; Lysosomal alpha-mannosidase D peptide; Lysosomal alpha-mannosidase E peptide]
Gene: MAN2B1

Interactor 2: FBX6 (Q9NRD1)
F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2)
Gene: FBXO6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.714

Property	Details
Experiments	26186194, 28514442, 32409323, 33961781, 22268729
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030246 - carbohydrate binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1011 Hs			1 293
+	Hs
		135832 MA2B1_HUMAN (1-1011): 0: 1360: 100.00		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		830112 MA2A2_HUMAN (60-1004): 0: 945: 26.47		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		1344624 MA2B2_HUMAN (60-1007): 0: 854: 27.25		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		1356250 MA2B2_HUMAN (60-1007): 0: 854: 27.25		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17