HitPredict

Interactor 1: Q9V3C8 (Q9V3C8)
DShc protein (FI07258p) (SHC-adaptor protein)
Gene: Shc

Interactor 2: DOS (Q9VZZ9)
Protein daughter of sevenless
Gene: DOS

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22028469
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0008293 - torso signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 409 Dm			1 878
+	Hs
		666100 SHC1_HUMAN (5-395): 5.42e-100: 310: 36.95		GAB1_HUMAN (3-435): 6.55e-53: 198: 18.71
+	Mm
		957247 SHC1_MOUSE (5-395): 3.29e-99: 308: 37.05		GAB1_MOUSE (3-435): 2e-50: 191: 18.28
+	Hs
		666193 SHC1_HUMAN (5-395): 5.42e-100: 310: 36.95		GAB2_HUMAN (3-221): 8.97e-38: 153: 29.55
+	Mm
		957250 SHC1_MOUSE (5-395): 3.29e-99: 308: 37.05		GAB2_MOUSE (229-433): 7.83e-38: 153: 18.30
+	Mm
		957233 SHC1_MOUSE (5-395): 3.29e-99: 308: 37.05		Q3ZB59_MOUSE (229-433): 9.14e-38: 152: 18.30
+	Hs
		426958 FES_HUMAN (165-396): 5.39e-48: 176: 22.49		GAB1_HUMAN (3-435): 6.55e-53: 198: 18.71
+	Hs
		1153427 GULP1_HUMAN (9-307): 8.54e-50: 172: 16.40		PKHA7_HUMAN (4-332): 1.36e-47: 185: 16.38
+	Hs
		275569 BCAR3_HUMAN (205-394): 8.64e-41: 156: 20.28		GAB1_HUMAN (3-435): 6.55e-53: 198: 18.71
+	Hs
		522965 SRC_HUMAN (163-404): 4.97e-41: 154: 21.26		GAB1_HUMAN (3-435): 6.55e-53: 198: 18.71
+	Hs
		433345 YES_HUMAN (179-404): 1.28e-40: 153: 18.91		GAB1_HUMAN (3-435): 6.55e-53: 198: 18.71
+	Hs
		442825 HCK_HUMAN (195-403): 5.74e-40: 151: 19.01		GAB1_HUMAN (3-435): 6.55e-53: 198: 18.71
+	Hs
		846468 BLK_HUMAN (182-403): 1.84e-39: 149: 18.46		GAB1_HUMAN (3-435): 6.55e-53: 198: 18.71
+	Hs
		548703 VAV_HUMAN (169-408): 9e-38: 147: 15.69		GAB1_HUMAN (3-435): 6.55e-53: 198: 18.71
+	Mm
		403466 SRC_MOUSE (177-404): 2.75e-40: 152: 21.25		GAB1_MOUSE (3-435): 2e-50: 191: 18.28
+	Hs
		433388 YES_HUMAN (179-404): 1.28e-40: 153: 18.91		PKHA7_HUMAN (4-332): 1.36e-47: 185: 16.38
+	Hs
		523086 SRC_HUMAN (163-404): 4.97e-41: 154: 21.26		GAB3_HUMAN (3-506): 1.23e-47: 181: 16.85
+	Hs
		412280 FYN_HUMAN (155-387): 9.5e-41: 153: 15.04		GAB3_HUMAN (3-506): 1.23e-47: 181: 16.85
+	Hs
		523213 SRC_HUMAN (163-404): 4.97e-41: 154: 21.26		GAB2_HUMAN (3-221): 8.97e-38: 153: 29.55
+	Hs
		1268502 ANS1A_HUMAN (11-251): 8.63e-40: 153: 13.58		DEFI6_HUMAN (1-436): 7.67e-36: 146: 14.54
+	Hs
		442830 HCK_HUMAN (195-403): 5.74e-40: 151: 19.01		RASA3_HUMAN (4-286): 6.27e-36: 148: 14.09