HitPredict

Interactor 1: PSMD6 (Q9V3G7)
26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit S10) (Protein Rpn7)
Gene: Rpn7

Interactor 2: PSMD1 (Q9V3P6)
26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory complex subunit p110) (26S proteasome regulatory subunit RPN2)
Gene: Rpn2

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005838 - proteasome regulatory particle GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 389 Dm			1 1020
+	Hs
		1062862 PSMD6_HUMAN (1-389): 1.37e-143: 414: 70.18		PSMD1_HUMAN (3-1001): 0: 1176: 60.30
+	Hs
		706 PSMD6_HUMAN (1-389): 1.37e-143: 414: 70.18		A0A087WW66_HUMAN (3-1001): 0: 1100: 57.50
+	Dm
		1180713 PSD11_DROME (5-388): 9.93e-80: 253: 13.63		PSMD1_DROME (1-1004): 0: 1198: 100.00
+	Hs
		121840 PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53		PSMD1_HUMAN (3-1001): 0: 1176: 60.30
+	Hs
		677 PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53		A0A087WW66_HUMAN (3-1001): 0: 1100: 57.50
+	Sc
		693366 RPN7_YEAST (15-389): 8.21e-95: 291: 33.83		RPN2_YEAST (1-1016): 0: 950: 35.74
+	Sc
		693378 RPN6_YEAST (29-383): 2.71e-75: 241: 10.80		RPN2_YEAST (1-1016): 0: 950: 35.74
+	Hs
		1027653 PSMD6_HUMAN (1-389): 1.37e-143: 414: 70.18		PSMD2_HUMAN (9-812): 0: 757: 16.90
+	Hs
		121748 PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53		PSMD2_HUMAN (9-812): 0: 757: 16.90
+	Dm
		1358535 PSMD6_DROME (1-389): 6.71e-134: 390: 100.00		Q9VW54_DROME (13-812): 0: 617: 17.03
+	At
		1275272 PSMD6_ARATH (12-389): 8.9e-128: 374: 50.79		PSD2A_ARATH (9-812): 0: 624: 15.16
+	Sp
		953207 RPN7_SCHPO (16-387): 7.39e-104: 314: 40.84		RPN1_SCHPO (9-810): 0: 574: 16.86
+	Dm
		1180725 PSD11_DROME (5-388): 9.93e-80: 253: 13.63		Q9VW54_DROME (13-812): 0: 617: 17.03
+	At
		1338956 PSD11_ARATH (30-388): 4.24e-75: 240: 13.06		PSD2A_ARATH (9-812): 0: 624: 15.16
+	Sp
		953211 RPN6_SCHPO (5-389): 2.86e-75: 241: 12.66		RPN1_SCHPO (9-810): 0: 574: 16.86
+	Sc
		753956 RPN7_YEAST (15-389): 8.21e-95: 291: 33.83		RPN1_YEAST (9-619): 8.39e-106: 355: 14.66
+	Sc
		753987 RPN6_YEAST (29-383): 2.71e-75: 241: 10.80		RPN1_YEAST (9-619): 8.39e-106: 355: 14.66