HitPredict

Interactor 1: PSMD6 (Q9V3G7)
26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit S10) (Protein Rpn7)
Gene: Rpn7

Interactor 2: Q9V3W9 (Q9V3W9)
UV excision repair protein RAD23
Gene: Rad23

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22364263
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RPN7~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 389 Dm			1 414
+	Rn
		1117340 Q6PCT9_RAT (1-389): 4.97e-143: 413: 69.67		RD23B_RAT (1-414): 8.97e-92: 284: 35.64
+	Hs
		872268 PSMD6_HUMAN (1-389): 1.37e-143: 414: 70.18		RD23B_HUMAN (1-414): 1.48e-87: 273: 34.97
+	Hs
		872158 PSMD6_HUMAN (1-389): 1.37e-143: 414: 70.18		RD23A_HUMAN (3-414): 5.11e-80: 252: 37.65
+	Hs
		1062848 PSMD6_HUMAN (1-389): 1.37e-143: 414: 70.18		DDI1_HUMAN (1-356): 2.63e-51: 179: 12.00
+	Rn
		78168 B5DEP6_RAT (3-388): 3.79e-83: 261: 13.53		RD23B_RAT (1-414): 8.97e-92: 284: 35.64
+	Dm
		1358537 PSMD6_DROME (1-389): 6.71e-134: 390: 100.00		Q9VWD9_DROME (1-406): 1.29e-37: 145: 10.06
+	Hs
		923997 PSMD6_HUMAN (1-389): 1.37e-143: 414: 70.18		RS27A_HUMAN (1-86): 3.64e-32: 121: 31.40
+	Hs
		121715 PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53		RD23B_HUMAN (1-414): 1.48e-87: 273: 34.97
+	Sc
		697117 RPN7_YEAST (15-389): 8.21e-95: 291: 33.83		RAD23_YEAST (2-413): 4.34e-71: 230: 24.83
+	Hs
		121714 PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53		RD23A_HUMAN (3-414): 5.11e-80: 252: 37.65
+	Hs
		1062897 PSMD6_HUMAN (1-389): 1.37e-143: 414: 70.18		UBQL1_HUMAN (206-410): 1.91e-17: 86.2: 14.72
+	Hs
		1062884 PSMD6_HUMAN (1-389): 1.37e-143: 414: 70.18		UBQL4_HUMAN (113-410): 3.13e-15: 79.6: 11.28
+	Sc
		697128 RPN6_YEAST (29-383): 2.71e-75: 241: 10.80		RAD23_YEAST (2-413): 4.34e-71: 230: 24.83
+	Hs
		121821 PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53		DDI1_HUMAN (1-356): 2.63e-51: 179: 12.00
+	Dm
		1180727 PSD11_DROME (5-388): 9.93e-80: 253: 13.63		Q9VWD9_DROME (1-406): 1.29e-37: 145: 10.06
+	Hs
		121731 PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53		RL40_HUMAN (1-83): 1.82e-34: 126: 30.12
+	Hs
		121730 PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53		RS27A_HUMAN (1-86): 3.64e-32: 121: 31.40
+	Hs
		121871 PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53		UBQL1_HUMAN (206-410): 1.91e-17: 86.2: 14.72
+	Hs
		121863 PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53		UBQL4_HUMAN (113-410): 3.13e-15: 79.6: 11.28