HitPredict

Interactor 1: RAB5 (Q9V3I2)
Ras-related protein Rab5 (Drab5) (EC 3.6.5.2) (Small monomeric GTPase Rab5)
Gene: RAB5

Interactor 2: Q9VLB7 (Q9VLB7)
Rab GDP dissociation inhibitor
Gene: Gdi

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	25453831, 25242320
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005829 - cytosol GO:0008021 - synaptic vesicle GO:0016192 - vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 219 Dm			1 443
+	Hs
		592123 RAB5A_HUMAN (12-218): 9.25e-103: 297: 73.59		GDIA_HUMAN (1-440): 0: 678: 67.80
+	Hs
		678339 RAB5B_HUMAN (12-218): 1.87e-100: 291: 72.17		GDIA_HUMAN (1-440): 0: 678: 67.80
+	Hs
		592161 RAB5A_HUMAN (12-218): 9.25e-103: 297: 73.59		GDIB_HUMAN (1-440): 0: 670: 67.80
+	Hs
		838618 RAB5B_HUMAN (12-218): 1.87e-100: 291: 72.17		GDIB_HUMAN (1-440): 0: 670: 67.80
+	Mm
		838709 RAB1A_MOUSE (19-218): 5.53e-90: 264: 38.05		GDIA_MOUSE (1-440): 0: 680: 68.03
+	Hs
		678344 RAB1A_HUMAN (19-218): 5.53e-90: 264: 38.05		GDIA_HUMAN (1-440): 0: 678: 67.80
+	Hs
		678394 RAB1B_HUMAN (22-218): 1.48e-88: 260: 39.30		GDIA_HUMAN (1-440): 0: 678: 67.80
+	Hs
		838625 RAB1A_HUMAN (19-218): 5.53e-90: 264: 38.05		GDIB_HUMAN (1-440): 0: 670: 67.80
+	Hs
		678330 RAB5C_HUMAN (10-218): 4.87e-86: 255: 73.36		GDIA_HUMAN (1-440): 0: 678: 67.80
+	Hs
		838683 RAB1B_HUMAN (22-218): 1.48e-88: 260: 39.30		GDIB_HUMAN (1-440): 0: 670: 67.80
+	Ce
		954789 P91857_CAEEL (9-219): 2.32e-99: 288: 71.09		REP1_CAEEL (3-431): 7.09e-141: 414: 24.39
+	Hs
		592106 RAB5A_HUMAN (12-218): 9.25e-103: 297: 73.59		RAE2_HUMAN (4-67): 2.76e-13: 73.9: 39.06
+	Hs
		592103 RAB5A_HUMAN (12-218): 9.25e-103: 297: 73.59		RAE1_HUMAN (4-47): 1.12e-12: 71.9: 52.27
+	Hs
		622572 RAB5B_HUMAN (12-218): 1.87e-100: 291: 72.17		RAE1_HUMAN (4-47): 1.12e-12: 71.9: 52.27
+	Hs
		642723 RAB1A_HUMAN (19-218): 5.53e-90: 264: 38.05		RAE2_HUMAN (4-67): 2.76e-13: 73.9: 39.06
+	Hs
		622577 RAB1A_HUMAN (19-218): 5.53e-90: 264: 38.05		RAE1_HUMAN (4-47): 1.12e-12: 71.9: 52.27
+	Hs
		642743 RAB1B_HUMAN (22-218): 1.48e-88: 260: 39.30		RAE2_HUMAN (4-67): 2.76e-13: 73.9: 39.06
+	Hs
		622619 RAB1B_HUMAN (22-218): 1.48e-88: 260: 39.30		RAE1_HUMAN (4-47): 1.12e-12: 71.9: 52.27
+	Hs
		642710 RAB5C_HUMAN (10-218): 4.87e-86: 255: 73.36		RAE2_HUMAN (4-67): 2.76e-13: 73.9: 39.06
+	Hs
		622565 RAB5C_HUMAN (10-218): 4.87e-86: 255: 73.36		RAE1_HUMAN (4-47): 1.12e-12: 71.9: 52.27