HitPredict

Interactor 1: RAB5 (Q9V3I2)
Ras-related protein Rab5 (Drab5) (EC 3.6.5.2) (Small monomeric GTPase Rab5)
Gene: RAB5

Interactor 2: Q9VPL5 (Q9VPL5)
LD27216p (TBC1 domain family member 15/17, isoform A) (TBC1 domain family member 15/17, isoform B) (TBC1 domain family member 15/17, isoform C)
Gene: Tbc1d15-17

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	25453831
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 219 Dm			1 715
+	Hs
		592392 RAB5A_HUMAN (12-218): 9.25e-103: 297: 73.59		TBC15_HUMAN (38-706): 5.7e-162: 485: 29.67
+	Hs
		895369 RAB5B_HUMAN (12-218): 1.87e-100: 291: 72.17		TBC15_HUMAN (38-706): 5.7e-162: 485: 29.67
+	Hs
		592503 RAB5A_HUMAN (12-218): 9.25e-103: 297: 73.59		TBC17_HUMAN (36-705): 3.56e-151: 455: 30.00
+	Hs
		895381 RAB5B_HUMAN (12-218): 1.87e-100: 291: 72.17		TBC17_HUMAN (36-705): 3.56e-151: 455: 30.00
+	Hs
		844641 RAB5C_HUMAN (10-218): 4.87e-86: 255: 73.36		TBC15_HUMAN (38-706): 5.7e-162: 485: 29.67
+	Hs
		918951 RAB1A_HUMAN (19-218): 5.53e-90: 264: 38.05		TBC17_HUMAN (36-705): 3.56e-151: 455: 30.00
+	Hs
		844743 RAB5C_HUMAN (10-218): 4.87e-86: 255: 73.36		TBC17_HUMAN (36-705): 3.56e-151: 455: 30.00
+	Os
		1130875 Q84TA8_ORYSJ (25-218): 2.52e-85: 253: 34.65		Q5SMT0_ORYSJ (35-676): 8.36e-126: 391: 27.92
+	Hs
		592528 RAB5A_HUMAN (12-218): 9.25e-103: 297: 73.59		TB22B_HUMAN (160-644): 1.93e-91: 296: 16.31
+	Hs
		592434 RAB5A_HUMAN (12-218): 9.25e-103: 297: 73.59		SGSM3_HUMAN (250-653): 8.18e-78: 266: 16.34
+	Hs
		895374 RAB5B_HUMAN (12-218): 1.87e-100: 291: 72.17		SGSM3_HUMAN (250-653): 8.18e-78: 266: 16.34
+	Hs
		233036 RB11A_HUMAN (19-219): 4.5e-85: 252: 38.32		TBC12_HUMAN (197-663): 2.25e-91: 303: 18.79
+	Hs
		914391 RB11A_HUMAN (19-219): 4.5e-85: 252: 38.32		TB22B_HUMAN (160-644): 1.93e-91: 296: 16.31
+	Hs
		1079972 RB11B_HUMAN (19-219): 2.81e-85: 253: 37.04		TBC14_HUMAN (208-642): 3.74e-86: 287: 16.89
+	Hs
		914423 RB11A_HUMAN (19-219): 4.5e-85: 252: 38.32		TBC14_HUMAN (208-642): 3.74e-86: 287: 16.89
+	Hs
		914176 RB11A_HUMAN (19-219): 4.5e-85: 252: 38.32		TBCD1_HUMAN (199-713): 9.47e-82: 284: 15.87
+	Hs
		234378 RB11B_HUMAN (19-219): 2.81e-85: 253: 37.04		EVI5_HUMAN (221-708): 4.36e-80: 274: 12.58
+	Hs
		234370 RB11A_HUMAN (19-219): 4.5e-85: 252: 38.32		EVI5_HUMAN (221-708): 4.36e-80: 274: 12.58
+	Hs
		844684 RAB5C_HUMAN (10-218): 4.87e-86: 255: 73.36		SGSM3_HUMAN (250-653): 8.18e-78: 266: 16.34
+	Sc
		350927 YPT1_YEAST (22-218): 6.88e-84: 249: 36.89		GYP1_YEAST (287-581): 1.66e-65: 230: 22.29