HitPredict

Interactor 1: NCBP2 (Q9V3L6)
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (CBP20)
Gene: Cbp20

Interactor 2: CPSF6 (Q9VSH4)
Cleavage and polyadenylation specificity factor subunit 6
Gene: CPSF6

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003729 - mRNA binding GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 154 Dm			1 652
+	Dm
		1364315 Q9VE52_DROME (18-152): 5.76e-35: 127: 25.93		CPSF6_DROME (1-652): 1.9e-57: 207: 100.00
+	Hs
		853881 NCBP2_HUMAN (5-146): 1.96e-40: 134: 76.06		PABP4_HUMAN (79-363): 3.01e-39: 155: 11.79
+	Hs
		516425 NCBP2_HUMAN (5-146): 1.96e-40: 134: 76.06		PABP1_HUMAN (79-364): 8.55e-34: 139: 13.29
+	Hs
		853912 NCBP2_HUMAN (5-146): 1.96e-40: 134: 76.06		CPSF6_HUMAN (1-556): 4.6e-33: 136: 35.89
+	Hs
		1084613 CSTFT_HUMAN (20-148): 9.73e-36: 131: 25.39		CPSF6_HUMAN (1-556): 4.6e-33: 136: 35.89
+	Hs
		703389 CSTF2_HUMAN (17-148): 4.51e-35: 129: 26.32		CPSF6_HUMAN (1-556): 4.6e-33: 136: 35.89
+	Hs
		1020249 ELAV2_HUMAN (3-130): 1.27e-23: 96.1: 18.46		PABP4_HUMAN (79-363): 3.01e-39: 155: 11.79
+	Hs
		1031344 ELAV1_HUMAN (11-113): 5.13e-23: 94.2: 22.86		PABP4_HUMAN (79-363): 3.01e-39: 155: 11.79
+	Hs
		257590 NCBP2_HUMAN (5-146): 1.96e-40: 134: 76.06		ANR17_HUMAN (166-481): 7.91e-25: 112: 17.93
+	Hs
		516495 PABP4_HUMAN (2-154): 5.03e-26: 104: 17.95		PABP1_HUMAN (79-364): 8.55e-34: 139: 13.29
+	Hs
		516339 PABP1_HUMAN (2-154): 8.03e-25: 101: 18.59		PABP1_HUMAN (79-364): 8.55e-34: 139: 13.29
+	Hs
		516689 PABP1_HUMAN (2-154): 8.03e-25: 101: 18.59		PABP3_HUMAN (79-364): 2.99e-33: 137: 12.59
+	Hs
		1073600 SF3B4_HUMAN (17-123): 8.49e-27: 105: 18.52		CPSF7_HUMAN (5-560): 2.66e-32: 132: 29.89
+	Hs
		516484 ELAV2_HUMAN (3-130): 1.27e-23: 96.1: 18.46		PABP1_HUMAN (79-364): 8.55e-34: 139: 13.29
+	Hs
		1077379 ELAV1_HUMAN (11-113): 5.13e-23: 94.2: 22.86		CPSF6_HUMAN (1-556): 4.6e-33: 136: 35.89
+	Hs
		1077418 ELAV1_HUMAN (11-113): 5.13e-23: 94.2: 22.86		CPSF7_HUMAN (5-560): 2.66e-32: 132: 29.89
+	Hs
		516518 RBM39_HUMAN (10-150): 1.57e-18: 83: 16.34		PABP1_HUMAN (79-364): 8.55e-34: 139: 13.29
+	Hs
		123882 NCBP2_HUMAN (5-146): 1.96e-40: 134: 76.06		SPT5H_HUMAN (43-262): 1.73e-09: 63.2: 14.29
+	Hs
		297862 SF3B4_HUMAN (17-123): 8.49e-27: 105: 18.52		SC24D_HUMAN (180-421): 8.63e-15: 80.5: 16.11