HitPredict

Interactor 1: NELFB (Q8WX92)
Negative elongation factor B (NELF-B) (Cofactor of BRCA1)
Gene: NELFB

Interactor 2: NELFA (Q9H3P2)
Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein)
Gene: NELFA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.748

The method score is based on:

Property Details
Experiments 24981860, 26496610, 28514442, 12612062, 33961781, 20305087, unassigned3799
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0032021 - NELF complex
GO:0034244 - negative regulation of transcription elongation by RNA polymerase II
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 580
Hs

1 528
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025