Interactor 1: UBA3 (Q9V6U8)
Nedd8-activating enzyme E1 catalytic subunit (EC 6.2.1.64) (Ubiquitin-activating enzyme 3 homolog)
Gene: UBA3

Interactor 2: ULA1 (Q9VTE9)
Nedd8-activating enzyme E1 regulatory subunit (Beta-amyloid precursor binding protein 1) (dAPP-BP1)
Gene: APP-BP1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.775

The method score is based on:

Property Details
Experiments 14605208, 21931660
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains E2_bind~ThiF, ThiF~ThiF
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0019781 - NEDD8 activating enzyme activity
GO:0032991 - protein-containing complex
GO:0045116 - protein neddylation
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 450
Dm

1 524
+ Hs
+ Ce
+ Hs
+ Hs
+ Sc
+ Sc
+ Hs
+ Sc
+ Dm
+ Dm
+ Oc
+ Hs
+ Sc
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024