HitPredict

Interactor 1: Q9VB22 (Q9VB22)
LD33695p (Partner of inscuteable) (Pins protein) (RE22964p)
Gene: pins

Interactor 2: Q9W2R4 (Q9W2R4)
Inscuteable
Gene: insc

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	1.00	0.953

Property	Details
Experiments	22253744, 10753746, 10693757, 22171003, 23354166, 29523789
Identification Methods	affinity chromatography technology, two hybrid, pull down, x-ray crystallography
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Insc_C~TPR_12, Insc_C~TPR_7
Common GO terms	GO:0000132 - establishment of mitotic spindle orientation GO:0005938 - cell cortex GO:0045179 - apical cortex GO:0055059 - asymmetric neuroblast division
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 658 Dm			1 859
+	Dm
		1097618 Q9NFR7_DROME (1-658): 4.76e-128: 394: 99.39		Q24367_DROME (1-859): 0: 1315: 99.65
+	Hs
		946369 GPSM2_HUMAN (136-638): 6.67e-34: 139: 20.87		INSC_HUMAN (308-766): 0: 535: 23.62
+	Hs
		1093079 GPSM1_HUMAN (2-176): 1.07e-20: 98.6: 22.03		INSC_HUMAN (308-766): 0: 535: 23.62