HitPredict

Interactor 1: Q9VCD5 (Q9VCD5)
UV excision repair protein RAD23
Gene: DmelCG10694

Interactor 2: Q9VWD9 (Q9VWD9)
LD38919p (Ubiquilin, isoform A) (Ubiquilin, isoform B)
Gene: Ubqn

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	19079254
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UBA~UBA, UBA~ubiquitin, ubiquitin~ubiquitin, UBA~XPC-binding
Common GO terms	GO:0005829 - cytosol GO:0031593 - polyubiquitin modification-dependent protein binding GO:0070628 - proteasome binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 290 Dm			1 547
+	Hs
		872229 RD23A_HUMAN (1-289): 5.67e-77: 240: 24.93		UBQL1_HUMAN (7-539): 6.9e-125: 380: 44.83
+	Hs
		872226 RD23A_HUMAN (1-289): 5.67e-77: 240: 24.93		UBQL2_HUMAN (5-539): 8.79e-116: 358: 39.43
+	Hs
		872222 RD23A_HUMAN (1-289): 5.67e-77: 240: 24.93		UBQL4_HUMAN (9-539): 1.18e-108: 338: 41.67
+	Mm
		1246842 UBQL1_MOUSE (1-258): 7.33e-56: 191: 16.11		UBQL2_MOUSE (7-539): 8.28e-114: 353: 40.50
+	Hs
		1345051 UBQL1_HUMAN (1-258): 7.41e-55: 188: 15.73		UBQL4_HUMAN (9-539): 1.18e-108: 338: 41.67
+	Hs
		872124 RD23A_HUMAN (1-289): 5.67e-77: 240: 24.93		RD23B_HUMAN (9-395): 4.27e-44: 163: 11.14
+	Hs
		803807 UBQL1_HUMAN (1-258): 7.41e-55: 188: 15.73		BAG6_HUMAN (2-497): 2.65e-57: 209: 14.15
+	Dm
		1362834 Q9VCD5_DROME (1-290): 4.81e-82: 250: 100.00		Q9VXF9_DROME (9-239): 1.31e-32: 131: 21.07
+	Hs
		872123 RD23A_HUMAN (1-289): 5.67e-77: 240: 24.93		RD23A_HUMAN (8-395): 3.15e-33: 132: 14.36
+	Sc
		697061 RAD23_YEAST (1-287): 5.83e-58: 192: 19.30		RAD23_YEAST (8-388): 4.32e-43: 160: 16.10
+	Dm
		574854 Q9VCD5_DROME (1-290): 4.81e-82: 250: 100.00		RL40_DROME (9-79): 4.82e-24: 99.2: 37.50
+	Hs
		872137 RD23A_HUMAN (1-289): 5.67e-77: 240: 24.93		RL40_HUMAN (9-91): 3.32e-24: 99: 35.71
+	Sp
		251965 RHP23_SCHPO (1-290): 3.81e-72: 228: 25.00		DSK2_SCHPO (7-194): 2.49e-20: 94.7: 23.08
+	Dm
		547946 Q9VCD5_DROME (1-290): 4.81e-82: 250: 100.00		RS27A_DROME (9-79): 8.33e-12: 65.3: 37.50
+	Sc
		697098 RAD23_YEAST (1-287): 5.83e-58: 192: 19.30		DSK2_YEAST (8-294): 2.96e-27: 115: 24.13
+	Hs
		872136 RD23A_HUMAN (1-289): 5.67e-77: 240: 24.93		RS27A_HUMAN (9-79): 8.33e-12: 65.3: 37.50
+	Hs
		924435 UBQL1_HUMAN (1-258): 7.41e-55: 188: 15.73		RL40_HUMAN (9-91): 3.32e-24: 99: 35.71
+	Dm
		547941 Q9V3W9_DROME (1-288): 5.54e-64: 208: 22.95		RS27A_DROME (9-79): 8.33e-12: 65.3: 37.50
+	Hs
		924216 UBQL1_HUMAN (1-258): 7.41e-55: 188: 15.73		RS27A_HUMAN (9-79): 8.33e-12: 65.3: 37.50