Interactor 1: DCR1 (Q9VCU9)
Endoribonuclease Dcr-1 (Protein dicer-1) (EC 3.1.26.3)
Gene: Dcr-1

Interactor 2: AGO2 (Q9VUQ5)
Protein argonaute-2
Gene: AGO2

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 12368261, 11498593
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ArgoL1~PAZ, ArgoL2~PAZ, PAZ~PAZ, PAZ~Piwi, PAZ~Ribonuclease_3
Common GO terms GO:0003727 - single-stranded RNA binding
GO:0004521 - RNA endonuclease activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 9 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 2249
Dm

1 1214
+ Dm
+ Dm
+ Dm
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Ce
+ Ce
+ Ce
+ Ce
+ Ce
+ Dm
+ Mm
+ Dr
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024