Interactor 1: TOPB1 (Q92547)
DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1)
Gene: TOPBP1
Interactor 2: FANCJ (Q9BX63)
Fanconi anemia group J protein (EC 5.6.2.3) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (DNA 5'-3' helicase FANCJ)
Gene: BRIP1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 0.55 | 0.719 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23157317, 24573678, 16391231, 21127055, 20159562, 30295604, 33010150, 33503405 |
| Identification Methods | affinity chromatography technology, x-ray crystallography, pull down, proximity labelling technology |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000077 - DNA damage checkpoint signaling GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 3 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
