HitPredict

Interactor 1: FLNA (Q9VEN1)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Filamin-1) (Filamin1)
Gene: cher

Interactor 2: Q9VXR3 (Q9VXR3)
HECT-type E3 ubiquitin transferase (EC 2.3.2.26)
Gene: HUWE1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	25294943
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 2210 Dm			1 5146
+	Dm
		1364782 FLNA_DROME (1-2210): 0: 1984: 100.00		Q9W325_DROME (4719-5144): 8.17e-176: 550: 34.27
+	Dm
		89901 FLNA_DROME (1-2210): 0: 1984: 100.00		D5SHR3_DROME (4727-5144): 4.53e-175: 548: 34.92
+	Hs
		125152 FLNA_HUMAN (224-2080): 0: 731: 27.18		WWP2_HUMAN (4252-5144): 0: 694: 23.03
+	Hs
		261331 FLNB_HUMAN (240-2080): 0: 724: 26.62		SMUF2_HUMAN (4547-5143): 0: 630: 29.71
+	Hs
		598332 FLNA_HUMAN (224-2080): 0: 731: 27.18		SMUF1_HUMAN (4587-5143): 0: 610: 30.12
+	Hs
		1052944 FLNC_HUMAN (223-2080): 0: 695: 26.24		SMUF2_HUMAN (4547-5143): 0: 630: 29.71
+	Hs
		963426 SPTB2_HUMAN (1-270): 4.59e-99: 359: 32.62		SMUF1_HUMAN (4587-5143): 0: 610: 30.12
+	Hs
		521619 ACTN1_HUMAN (2-265): 1.45e-99: 345: 30.97		SMUF1_HUMAN (4587-5143): 0: 610: 30.12
+	Mm
		1143711 SPTB2_MOUSE (1-270): 4.59e-99: 359: 32.62		HUWE1_MOUSE (1-499): 1.2e-159: 563: 44.08
+	Hs
		957567 PGBM_HUMAN (886-2174): 4.28e-99: 360: 11.93		HERC5_HUMAN (4474-5144): 4.97e-165: 542: 18.82
+	Hs
		1350503 MACF1_HUMAN (3-235): 1.9e-32: 141: 37.13		HECW2_HUMAN (3925-5145): 0: 619: 18.59
+	Hs
		1264807 TITIN_HUMAN (247-828): 8.1e-14: 80.1: 10.41		SMUF2_HUMAN (4547-5143): 0: 630: 29.71
+	Hs
		506823 SPTB1_HUMAN (1-309): 7.02e-99: 358: 26.75		HUWE1_HUMAN (3086-3641): 3.4e-09: 66.2: 12.33
+	Hs
		255891 OBSL1_HUMAN (1438-2208): 5e-17: 90.5: 12.19		HUWE1_HUMAN (3086-3641): 3.4e-09: 66.2: 12.33