HitPredict - High confidence protein-protein interactions

Interactor 1: RDX (Q9VFP2)
Protein roadkill (Hh-induced MATH and BTB domain-containing protein)
Gene: RDX

Interactor 2: RDX (Q9VFP2)
Protein roadkill (Hh-induced MATH and BTB domain-containing protein)
Gene: RDX

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	26263855, 19955409
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BTB~BTB, MATH~MATH
Common GO terms	GO:0001654 - eye development GO:0001745 - compound eye morphogenesis GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 15 others more... GO:0007367 - segment polarity determination GO:0016567 - protein ubiquitination GO:0030162 - regulation of proteolysis GO:0031463 - Cul3-RING ubiquitin ligase complex GO:0031625 - ubiquitin protein ligase binding GO:0031648 - protein destabilization GO:0042308 - negative regulation of protein import into nucleus GO:0042803 - protein homodimerization activity GO:0043065 - positive regulation of apoptotic process GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:0045732 - positive regulation of protein catabolic process GO:0045879 - negative regulation of smoothened signaling pathway GO:0046330 - positive regulation of JNK cascade GO:0070936 - protein K48-linked ubiquitination GO:1990756 - ubiquitin-like ligase-substrate adaptor activity
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1	829
Dm

1	829

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Last updated: 15 Jul 2024