HitPredict

Interactor 1: PFD3 (Q9VGP6)
Prefoldin subunit 3 (Protein merry-go-round) (von Hippel-Lindau-binding protein 1)
Gene: mgr

Interactor 2: PFD2 (Q9VTE5)
Probable prefoldin subunit 2
Gene: Pfdn2

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	1.00	0.821

Property	Details
Experiments	27025979, 22036573, 14605208
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Prefoldin~Prefoldin_2
Common GO terms	GO:0005737 - cytoplasm GO:0006457 - protein folding GO:0016272 - prefoldin complex GO:0045196 - establishment or maintenance of neuroblast polarity
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 194 Dm			1 143
+	Hs
		901756 PFD3_HUMAN (1-189): 1.01e-82: 245: 50.52		PFD2_HUMAN (5-141): 5.34e-43: 140: 48.55
+	Dm
		1250580 Q8T965_DROME (1-180): 3.2e-66: 202: 28.57		PFD2_DROME (1-143): 6.81e-50: 157: 100.00
+	Hs
		1151022 Q6FH24_HUMAN (36-189): 5.85e-69: 208: 54.14		PFD2_HUMAN (5-141): 5.34e-43: 140: 48.55
+	Sc
		766524 PFD3_YEAST (17-192): 5.42e-64: 197: 35.64		PFD2_YEAST (14-117): 1.03e-25: 95.5: 32.69