Interactor 1: GPI8 (Q92643)
GPI-anchor transamidase (EC 2.6.1.-) (GPI-anchor transamidase component PIGK, catalytic subunit) (GPI8 homolog) (hGPI8) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K)
Gene: PIGK

Interactor 2: PIGT (Q969N2)
GPI-anchor transamidase component PIGT (Phosphatidylinositol-glycan biosynthesis class T protein)
Gene: PIGT

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.964

The method score is based on:

Property Details
Experiments 33961781, 26186194, 28514442, 12582175, 11483512, 12802054, unassigned3799
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Gpi16~Peptidase_C13
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0006506 - GPI anchor biosynthetic process
GO:0016020 - membrane
GO:0016255 - attachment of GPI anchor to protein
GO:0042765 - GPI-anchor transamidase complex
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 395
Hs

1 578
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025