HitPredict

Interactor 1: DLK1 (O01700)
Mitogen-activated protein kinase kinase kinase dlk-1 (EC 2.7.11.25) (DAP kinase-like kinase) (Death-associated protein kinase-like kinase)
Gene: dlk-1

Interactor 2: Q33BL4 (Q33BL4)
Protein kinase domain-containing protein
Gene: frm-5.1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	21110867
Identification Methods	two hybrid pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016310 - phosphorylation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 928 Ce			1 1551
+	Hs
		337601 ABL1_HUMAN (10-879): 4.95e-124: 405: 17.42		E41L3_HUMAN (578-1360): 9.05e-90: 319: 11.42
+	Dm
		448235 INSR_DROME (126-821): 7.72e-115: 390: 18.95		MOEH_DROME (683-1083): 1.55e-95: 322: 16.83
+	Hs
		647967 MARK3_HUMAN (78-782): 3.86e-127: 403: 17.03		E41LA_HUMAN (682-1373): 7.75e-89: 307: 14.47
+	Hs
		647901 MARK3_HUMAN (78-782): 3.86e-127: 403: 17.03		PTN14_HUMAN (688-1039): 8.95e-85: 305: 20.90
+	Hs
		546938 MARK3_HUMAN (78-782): 3.86e-127: 403: 17.03		EZRI_HUMAN (681-1165): 3.02e-87: 299: 14.40
+	Hs
		1233547 MINK1_HUMAN (112-868): 5.88e-116: 387: 15.30		E41LA_HUMAN (682-1373): 7.75e-89: 307: 14.47
+	Hs
		523042 SRC_HUMAN (5-388): 9.72e-117: 369: 21.52		FRMD5_HUMAN (674-1105): 1.09e-95: 322: 16.59
+	Hs
		523221 SRC_HUMAN (5-388): 9.72e-117: 369: 21.52		E41L3_HUMAN (578-1360): 9.05e-90: 319: 11.42
+	Hs
		412416 FYN_HUMAN (3-388): 3.6e-116: 367: 19.81		E41L3_HUMAN (578-1360): 9.05e-90: 319: 11.42
+	Hs
		547137 MINK1_HUMAN (112-868): 5.88e-116: 387: 15.30		EZRI_HUMAN (681-1165): 3.02e-87: 299: 14.40
+	Hs
		1183129 MARK2_HUMAN (75-773): 8.72e-117: 377: 16.39		E41LA_HUMAN (682-1373): 7.75e-89: 307: 14.47
+	Hs
		547111 MARK2_HUMAN (75-773): 8.72e-117: 377: 16.39		EZRI_HUMAN (681-1165): 3.02e-87: 299: 14.40
+	Hs
		411855 LCK_HUMAN (5-390): 4.5e-116: 366: 20.98		E41L1_HUMAN (633-1392): 7.2e-88: 309: 12.47
+	Hs
		411734 LCK_HUMAN (5-390): 4.5e-116: 366: 20.98		PTN14_HUMAN (688-1039): 8.95e-85: 305: 20.90
+	Hs
		433240 YES_HUMAN (3-388): 1.6e-117: 371: 20.44		EZRI_HUMAN (681-1165): 3.02e-87: 299: 14.40
+	Hs
		337358 ABL1_HUMAN (10-879): 4.95e-124: 405: 17.42		PTN4_HUMAN (1254-1547): 1.24e-13: 78.2: 7.62
+	Hs
		647882 MARK3_HUMAN (78-782): 3.86e-127: 403: 17.03		PTN13_HUMAN (1016-1375): 9.97e-14: 79: 14.01
+	Hs
		337554 ABL1_HUMAN (10-879): 4.95e-124: 405: 17.42		GRIP2_HUMAN (1361-1535): 8.98e-09: 62.4: 29.57
+	Hs
		412035 FYN_HUMAN (3-388): 3.6e-116: 367: 19.81		PTN4_HUMAN (1254-1547): 1.24e-13: 78.2: 7.62
+	Hs
		411696 LCK_HUMAN (5-390): 4.5e-116: 366: 20.98		PTN13_HUMAN (1016-1375): 9.97e-14: 79: 14.01