HitPredict

Interactor 1: NC2B (Q9VJQ5)
Protein Dr1 (Down-regulator of transcription 1) (Negative cofactor 2-beta) (NC2-beta) (dNC2)
Gene: NC2beta

Interactor 2: Q9W2E3 (Q9W2E3)
Negative cofactor 2alpha
Gene: NC2alpha

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.812

The method score is based on:

Property Details
Experiments 30995488, 14605208
Identification Methods two hybrid, pull down, protein complementation assay
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CBFD_NFYB_HMF~CBFD_NFYB_HMF
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001046 - core promoter sequence-specific DNA binding
GO:0005634 - nucleus
GO:0016251 - RNA polymerase II general transcription initiation factor activity
GO:0017054 - negative cofactor 2 complex
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 183
Dm

1 341
+ Dm
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ Dm

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Last updated: 15 Jul 2024