HitPredict

Interactor 1: Q9VKW8 (Q9VKW8)
U6 snRNA-associated Sm-like protein LSm4
Gene: CG5356

Interactor 2: Q9W087 (Q9W087)
U6 snRNA-associated Sm-like protein LSm8
Gene: l(3)neo7

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	1.00	0.821

Property	Details
Experiments	22036573, 14605208, 20353594
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005688 - U6 snRNP GO:0046540 - U4/U6 x U5 tri-snRNP complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 154 Dm			1 95
+	Dm
		1368675 Q9VKW8_DROME (1-154): 6.76e-64: 194: 100.00		Q9VJI7_DROME (4-74): 1.82e-20: 80.3: 26.32
+	Hs
		321444 LSM4_HUMAN (1-88): 1.03e-40: 134: 88.64		LSM8_HUMAN (2-95): 1.25e-33: 113: 69.15
+	Hs
		167728 LSM4_HUMAN (1-88): 1.03e-40: 134: 88.64		LSM1_HUMAN (2-90): 3.41e-25: 93: 26.97
+	Hs
		928049 LSM4_HUMAN (1-88): 1.03e-40: 134: 88.64		RSMN_HUMAN (2-75): 3.88e-24: 93: 31.33
+	Hs
		539204 LSM4_HUMAN (1-88): 1.03e-40: 134: 88.64		RSMB_HUMAN (2-75): 1.3e-23: 91.4: 31.33
+	Hs
		1356296 LSM4_HUMAN (1-88): 1.03e-40: 134: 88.64		LSM7_HUMAN (4-74): 1.57e-23: 87.6: 29.33
+	Hs
		321390 SMD3_HUMAN (2-105): 3.32e-30: 107: 31.73		LSM8_HUMAN (2-95): 1.25e-33: 113: 69.15
+	Hs
		321389 SMD1_HUMAN (1-90): 1.1e-29: 106: 27.96		LSM8_HUMAN (2-95): 1.25e-33: 113: 69.15
+	Ce
		1091044 LSM4_CAEEL (1-82): 8.35e-36: 122: 76.83		Q23543_CAEEL (4-74): 1.93e-21: 82.6: 30.67
+	Hs
		912611 SMD3_HUMAN (2-105): 3.32e-30: 107: 31.73		RSMN_HUMAN (2-75): 3.88e-24: 93: 31.33
+	Hs
		167682 SMD1_HUMAN (1-90): 1.1e-29: 106: 27.96		LSM1_HUMAN (2-90): 3.41e-25: 93: 26.97
+	Hs
		538896 SMD3_HUMAN (2-105): 3.32e-30: 107: 31.73		RSMB_HUMAN (2-75): 1.3e-23: 91.4: 31.33
+	Dm
		218359 SMD3_DROME (2-105): 1.45e-29: 107: 29.81		RSMB_DROME (3-69): 1.38e-23: 90.7: 32.88
+	Hs
		538894 SMD1_HUMAN (1-90): 1.1e-29: 106: 27.96		RSMB_HUMAN (2-75): 1.3e-23: 91.4: 31.33
+	Hs
		912752 SMD3_HUMAN (2-105): 3.32e-30: 107: 31.73		LSM7_HUMAN (4-74): 1.57e-23: 87.6: 29.33
+	Hs
		912024 SMD3_HUMAN (2-105): 3.32e-30: 107: 31.73		RUXG_HUMAN (4-74): 1.42e-21: 81.8: 29.58
+	Dm
		218371 SMD3_DROME (2-105): 1.45e-29: 107: 29.81		Q9VJI7_DROME (4-74): 1.82e-20: 80.3: 26.32
+	Dm
		218379 SMD3_DROME (2-105): 1.45e-29: 107: 29.81		RUXG_DROME (4-74): 5.83e-21: 80.3: 25.35
+	Hs
		68411 SMD3_HUMAN (2-105): 3.32e-30: 107: 31.73		RUXGL_HUMAN (4-74): 1.04e-19: 77.2: 29.58
+	Hs
		68409 SMD1_HUMAN (1-90): 1.1e-29: 106: 27.96		RUXGL_HUMAN (4-74): 1.04e-19: 77.2: 29.58