HitPredict

Interactor 1: WASC3 (O01901)
WASH complex subunit homolog 3 (Daf-16-dependent longevity protein 1)
Gene: ddl-1

Interactor 2: WASH1 (O18195)
WASH complex subunit homolog 1
Gene: ddl-2

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.680

Property	Details
Experiments	19123269, 22265419, 14704431
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, two hybrid pooling approach, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006887 - exocytosis GO:0008340 - determination of adult lifespan GO:0010468 - regulation of gene expression GO:0051220 - cytoplasmic sequestering of protein GO:0071203 - WASH complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 189 Ce			1 497
+	Hs
		66322 WASC3_HUMAN (10-175): 6.78e-72: 217: 25.58		WASH1_HUMAN (2-497): 1.34e-156: 455: 23.65
+	Hs
		86517 WASC3_HUMAN (10-175): 6.78e-72: 217: 25.58		WASH3_HUMAN (2-497): 1.12e-151: 442: 23.85
+	Hs
		1343249 WASC3_HUMAN (10-175): 6.78e-72: 217: 25.58		WASH6_HUMAN (40-497): 3.74e-131: 389: 22.82
+	Dm
		1177496 WASC3_DROME (1-162): 8e-72: 216: 26.95		WASH1_DROME (2-486): 5.18e-129: 385: 21.71