HitPredict

Interactor 1: Q9VMH2 (Q9VMH2)
Actin-related protein 2/3 complex subunit 4
Gene: Arpc4

Interactor 2: Q9VQD8 (Q9VQD8)
Actin-related protein 2/3 complex subunit 5
Gene: Arpc5

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.833

Property	Details
Experiments	14605208, 22036573, 19079254
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	ARPC4~P16-Arc
Common GO terms	GO:0005200 - structural constituent of cytoskeleton GO:0005737 - cytoplasm GO:0005885 - Arp2/3 protein complex GO:0034314 - Arp2/3 complex-mediated actin nucleation GO:0051015 - actin filament binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 168 Dm			1 151
+	Hs
		887492 ARPC4_HUMAN (1-168): 1.54e-94: 273: 82.74		ARP5L_HUMAN (1-149): 3.48e-66: 199: 48.03
+	Hs
		181308 ARPC4_HUMAN (1-168): 1.54e-94: 273: 82.74		ARPC5_HUMAN (1-149): 1.09e-64: 196: 51.33
+	Sp
		1013757 ARPC4_SCHPO (1-168): 2.48e-86: 252: 64.88		ARPC5_SCHPO (9-148): 7.04e-52: 163: 29.53
+	At
		98335 ARPC4_ARATH (1-168): 5.73e-89: 258: 61.91		ARC5A_ARATH (22-148): 4.28e-48: 153: 34.88
+	Sc
		703302 ARPC4_YEAST (1-168): 1.17e-84: 247: 66.27		ARPC5_YEAST (10-149): 1.71e-45: 147: 24.67