HitPredict

Interactor 1: Q9VN02 (Q9VN02)
Charged multivesicular body protein 3 (Chromatin-modifying protein 3)
Gene: Vps24

Interactor 2: Q9Y162 (Q9Y162)
BcDNA.GH02678 (Vacuolar protein sorting 4, isoform A (EC 3.6.1.3)) (Vacuolar protein sorting 4, isoform B)
Gene: Vps4

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 223 Dm			1 442
+	Hs
		1357379 CHMP3_HUMAN (1-223): 7.31e-52: 168: 57.40		VPS4A_HUMAN (7-441): 3.49e-126: 374: 73.79
+	Mm
		804060 CHM2A_MOUSE (3-222): 2.47e-46: 154: 22.73		VPS4B_MOUSE (2-442): 7.61e-128: 378: 75.34
+	Hs
		208804 CHM2A_HUMAN (3-222): 2.42e-45: 152: 22.73		VPS4B_HUMAN (2-442): 5.26e-128: 379: 74.21
+	Dm
		1373132 Q9VRJ5_DROME (2-209): 1.68e-44: 149: 27.40		Q9Y162_DROME (1-442): 6.4e-129: 381: 100.00
+	Dm
		1362012 Q9VBI3_DROME (3-202): 5.98e-43: 147: 24.00		Q9Y162_DROME (1-442): 6.4e-129: 381: 100.00
+	Hs
		260164 CHM2B_HUMAN (9-204): 2.59e-44: 149: 22.45		VPS4B_HUMAN (2-442): 5.26e-128: 379: 74.21
+	Hs
		208869 CHM2A_HUMAN (3-222): 2.42e-45: 152: 22.73		VPS4A_HUMAN (7-441): 3.49e-126: 374: 73.79
+	Hs
		1357378 CHM2B_HUMAN (9-204): 2.59e-44: 149: 22.45		VPS4A_HUMAN (7-441): 3.49e-126: 374: 73.79
+	Dm
		1248702 Q8SXB1_DROME (15-202): 1.56e-38: 135: 22.34		Q9Y162_DROME (1-442): 6.4e-129: 381: 100.00
+	Dm
		1279493 Q95SH2_DROME (23-222): 2.92e-38: 133: 16.50		Q9Y162_DROME (1-442): 6.4e-129: 381: 100.00
+	Hs
		260156 CHM1A_HUMAN (22-223): 2.63e-37: 130: 11.88		VPS4B_HUMAN (2-442): 5.26e-128: 379: 74.21
+	Hs
		1336687 CHM1A_HUMAN (22-223): 2.63e-37: 130: 11.88		VPS4A_HUMAN (7-441): 3.49e-126: 374: 73.79
+	Hs
		260145 CHM1B_HUMAN (23-223): 3.02e-35: 125: 13.93		VPS4B_HUMAN (2-442): 5.26e-128: 379: 74.21
+	Sc
		732854 DID4_YEAST (3-222): 4.31e-50: 164: 21.78		VPS4_YEAST (1-442): 1.8e-112: 339: 57.66
+	Hs
		208865 CHM2A_HUMAN (3-222): 2.42e-45: 152: 22.73		SPAST_HUMAN (62-440): 1.51e-113: 348: 36.84
+	At
		1352475 VPS2A_ARATH (2-222): 7.13e-55: 176: 23.87		VPS4_ARATH (4-442): 9.6e-106: 322: 52.02
+	At
		1013169 VPS2B_ARATH (1-222): 9.82e-50: 163: 24.32		VPS4_ARATH (4-442): 9.6e-106: 322: 52.02
+	Sc
		732543 VPS24_YEAST (10-223): 2.51e-42: 144: 30.23		VPS4_YEAST (1-442): 1.8e-112: 339: 57.66
+	Hs
		1185555 CHM1B_HUMAN (23-223): 3.02e-35: 125: 13.93		SPAST_HUMAN (62-440): 1.51e-113: 348: 36.84
+	At
		1352776 CHM1B_ARATH (22-217): 4.85e-40: 137: 16.84		VPS4_ARATH (4-442): 9.6e-106: 322: 52.02