Interactor 1: PTPS (O02058)
Putative 6-pyruvoyl tetrahydrobiopterin synthase (PTP synthase) (PTPS) (EC 4.2.3.12)
Gene: ptps-1

Interactor 2: PTPS (O02058)
Putative 6-pyruvoyl tetrahydrobiopterin synthase (PTP synthase) (PTPS) (EC 4.2.3.12)
Gene: ptps-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.837

The method score is based on:

Property Details
Experiments 19123269, 14704431
Identification Methods two hybrid, two hybrid array, two hybrid pooling approach, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PTPS~PTPS
Common GO terms GO:0003874 - 6-pyruvoyltetrahydropterin synthase activity
GO:0005739 - mitochondrion
GO:0006729 - tetrahydrobiopterin biosynthetic process
GO:0046872 - metal ion binding
GO:0070497 - 6-carboxy-5,6,7,8-tetrahydropterin synthase activity
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 140
Ce

1 140
+ Dm
+ Hs
+ Mm
+ Ph

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Last updated: 15 Jul 2024